MicrobiologybioRxivPreprint
Staphylococcus aureus counters organic acid anion-mediated inhibition of peptidoglycan cross-linking through robust alanine racemase activity
Sasmita Panda, Yahani P. Jayasinghe, Dhananjay D. Shinde…·Vinai Chittezham Thomas
This study shows that Staphylococcus aureus counters acetate-mediated inhibition of peptidoglycan cross-linking by maintaining high intracellular D-Ala levels through alanine racemase and limiting D-Ala flux via D-alanine aminotransferase.