Developmental BiologybioRxivPreprint
Ventricular chamber-specific Pitx2 insufficiency leads to cardiac hypertrophy and arrhythmias
Ana Chinchilla, Francisco José Esteban, Estefanía Lozano-Velasco…·Diego Franco
This study shows that Pitx2 insufficiency in ventricular chambers causes cardiac hypertrophy, dilation, and electrophysiological defects similar to long QT syndrome.