BioengineeringbioRxivPreprint
Conditional fusogenic lipid nanocarriers for cytosolic delivery of macromolecular therapeutics
Qian Zhong, Edward K.W. Tan, Ananth Shyamal…·Sangeeta N. Bhatia
This paper develops C-FLIPs, protease-activated liposomes that deliver macromolecular therapeutics to the cytosol of cancer cells, inducing tumor regression and immune memory.