BiochemistryNature Structural & Molecular BiologyPeer-reviewed
Structural Determinants for Activity of the Antidepressant Vortioxetine at Human and Rodent 5-HT3 receptors
Uriel López-Sánchez, Lachlan Jake Munro, Lucy Kate Ladefoged…·Anders S. Kristensen
This study investigates how vortioxetine interacts with human and rodent 5-HT3 receptors, revealing structural differences and mechanisms of action.