Author

Andrei Alexeev

Complete Genomics (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 3 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:whole-genome sequencing· 4 Approach:experimental assay· 3 Research Focus:variant calling· 3 Research Focus:benchmarking· 2 Research Focus:database / resource· 2 Organism:human· 2 Research Focus:variant effect prediction· 2 Research Focus:deconvolution· 1

Frequent Co-Authors

Radoje Drmanac· 4 shared Ao CheniD· 3 shared Hanjie Shen· 3 shared Ou WangiD· 3 shared Wenwei ZhangiD· 3 shared Xun XuiD· 3 shared Yang Xi· 3 shared Yuan JiangiD· 3 shared

Activity by Year

2018-2019 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersGenomics

Radoje Drmanac

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Advanced Whole Genome Sequencing Using an Entirely PCR-free Massively Parallel Sequencing Workflow

Hanjie Shen, Pengjuan Liu, Zhanqing Li, Fang Chen, Hui Jiang, Shiming Shi, Yang Xi, Qiaoling Li, Xiaojue Wang, Jing Zhao, Xinming Liang, Yinlong Xie, Lin Wang, Wenlan Tian, Tam Berntsen, , Radoje Drmanac

This paper demonstrates that PCR-free whole genome sequencing using the DNBSEQ platform and machine learning variant calling significantly reduces InDel errors and improves variant calling performance.

bioRxiv · Dec 20, 2019 · PreprintGenomics

Development of Coupling Controlled Polymerizations by Adapter-ligation in Mate-pair Sequencing for Detection of Various Genomic Variants in One Single Assay

Zirui Dong, Xia Zhao, Qiaoling Li, Zhenjun Yang, Yang Xi, Andrei Alexeev, Hanjie Shen, Ou Wang, Jie Ruan, Han Ren, Hanmin Wei, Xiaojuan Qi, Jiguang Li, Xiaofan Zhu, Yanyan Zhang, , Yuan Jiang

This paper introduces a new mate-pair sequencing method called CP-AL that improves DNA-circularization efficiency and reduces contamination, enabling accurate detection of genomic variants.

DNA Research · May 8, 2019Peer-reviewedGenomics

Efficient long single molecule sequencing for cost effective and accurate sequencing, haplotyping, and de novo assembly

Ou Wang, Robert G. Chin, Xiaofang Cheng, Michelle Ka Yan Wu, Qing Mao, Jingbo Tang, Yuhui Sun, Ellis Anderson, Han K. Lam, Dan Chen, Yujun Zhou, Linying Wang, Fei Fan, Yan Zou, Yinlong Xie, , Brock A. Peters

This paper introduces stLFR, a low-cost method for long DNA sequencing that enables accurate variant calling, haplotyping, and de novo assembly.

Genome Research · May 1, 2019Peer-reviewedGenomics

3’ Branch Ligation: A Novel Method to Ligate Non-Complementary DNA to Recessed or Internal 3’OH Ends in DNA or RNA

Lin Wang, Yang Xi, Wenwei Zhang, Weimao Wang, Hanjie Shen, Xiaojue Wang, Xia Zhao, Andrei Alexeev, Brock A. Peters, Alayna Albert, Xu Xu, Han Yun Ren, Ou Wang, Killeen S. Kirkconnell, Helena Perazich, , Yuan Jiang

The paper introduces a novel ligation method called 3BL that allows non-complementary DNA to be ligated to 3' ends of DNA or RNA, improving NGS library construction by reducing adapter dimer issues and increasing yield.

DNA Research · Oct 5, 2018Peer-reviewedMolecular Biology