Author

Yang Xi

BGI Group (China)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Genomics· 3 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:whole-genome sequencing· 4 Approach:experimental assay· 3 Research Focus:benchmarking· 2 Research Focus:database / resource· 2 Research Focus:variant calling· 2 Assay:DNA methylation· 1 Research Focus:genome assembly· 1 Organism:human· 1

Frequent Co-Authors

Yuan JiangiD· 4 shared Andrei Alexeev· 3 shared Han Ren· 3 shared Hanjie Shen· 3 shared Radoje Drmanac· 3 shared Xun XuiD· 3 shared Ao CheniD· 2 shared Killeen S. Kirkconnell· 2 shared

Activity by Year

2018-2019 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersGenomics

Yuan JiangORCID

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4 papers

Recent·Most cited

Advanced Whole Genome Sequencing Using an Entirely PCR-free Massively Parallel Sequencing Workflow

Hanjie Shen, Pengjuan Liu, Zhanqing Li, Fang Chen, Hui Jiang, Shiming Shi, Yang Xi, Qiaoling Li, Xiaojue Wang, Jing Zhao, Xinming Liang, Yinlong Xie, Lin Wang, Wenlan Tian, Tam Berntsen, , Radoje Drmanac

This paper demonstrates that PCR-free whole genome sequencing using the DNBSEQ platform and machine learning variant calling significantly reduces InDel errors and improves variant calling performance.

bioRxiv · Dec 20, 2019 · PreprintGenomics

Development of Coupling Controlled Polymerizations by Adapter-ligation in Mate-pair Sequencing for Detection of Various Genomic Variants in One Single Assay

Zirui Dong, Xia Zhao, Qiaoling Li, Zhenjun Yang, Yang Xi, Andrei Alexeev, Hanjie Shen, Ou Wang, Jie Ruan, Han Ren, Hanmin Wei, Xiaojuan Qi, Jiguang Li, Xiaofan Zhu, Yanyan Zhang, , Yuan Jiang

This paper introduces a new mate-pair sequencing method called CP-AL that improves DNA-circularization efficiency and reduces contamination, enabling accurate detection of genomic variants.

DNA Research · May 8, 2019Peer-reviewedGenomics

Dynamic chromosome rearrangements of the white-spotted bamboo shark shed light on cartilaginous fish diversification mechanisms

Yaolei Zhang, Haoyang Gao, Hanbo Li, Jiao Guo, Meiniang Wang, Qiwu Xu, Jiahao Wang, Meiqi Lv, Xinyu Guo, Qun Liu, Likun Wei, Han Ren, Yang Xi, Yang Guo, Qian Zhao, , Xin Liu

The paper reports the chromosome-level genome of the white-spotted bamboo shark and shows chromosome rearrangements contribute to phenotypic diversity in cartilaginous fishes.

bioRxiv · Apr 8, 2019 · PreprintGenomics

3’ Branch Ligation: A Novel Method to Ligate Non-Complementary DNA to Recessed or Internal 3’OH Ends in DNA or RNA

Lin Wang, Yang Xi, Wenwei Zhang, Weimao Wang, Hanjie Shen, Xiaojue Wang, Xia Zhao, Andrei Alexeev, Brock A. Peters, Alayna Albert, Xu Xu, Han Yun Ren, Ou Wang, Killeen S. Kirkconnell, Helena Perazich, , Yuan Jiang

The paper introduces a novel ligation method called 3BL that allows non-complementary DNA to be ligated to 3' ends of DNA or RNA, improving NGS library construction by reducing adapter dimer issues and increasing yield.

DNA Research · Oct 5, 2018Peer-reviewedMolecular Biology