GeneticseLifePeer-reviewed
BICC1 Interacts with PKD1 and PKD2 to Drive Cystogenesis in ADPKD
Uyen Tran, Andrew J. Streets, Devon Smith…·Oliver Wessely
This study shows BICC1 interacts with PKD1 and PKD2, exacerbating ADPKD severity through RNA metabolism, using animal models, genetic studies, and human cohorts.