Cell BiologybioRxiv
Cigarette Smoke Activates NOTCH3 to Promote Goblet Cell Differentiation in Human Airway Epithelial Cells
Manish Bodas, Andrew R. Moore, Bharathiraja Subramaniyan…·Matthew S. Walters
This study shows that cigarette smoke activates NOTCH3, promoting goblet cell differentiation in human airway epithelial cells, contributing to COPD-related goblet cell metaplasia.
DOI 10.1165/rcmb.2020-0302oc