ImmunologybioRxivPreprint
Red Blood Cell Transfusion is a Non-Canonical Immune Stimulus Characterized by the Suboptimal Induction of CD4+ T Cell Help
Jelena Medved, Abhinav Arneja, Neha Shah…·Chance John Luckey
This study shows that RBC transfusion induces weak IgG class switching compared to vaccination, due to suboptimal T cell help, and activates T cells via a non-canonical pathway.
DOI 10.1101/2025.06.26.661795