Villin-SNAP25 interaction regulates insulin secretion downstream of ICA512 signaling
Hassan Mziaut, Preethi Kesavan, Chunguang Chen, Ali Gheisari, Jaber Dehghany, Andreas S. Mueller, Anke Sönmez, Katharina Ganß, Inna V. Kalaidzidis, Carla Münster, Matthias Lohmann, Yannis L. Kalaidzidis, Anke Schulte, Raphaël Scharfmann, Stefan Lehr, , Michele Solimena
This study shows that the Villin-SNAP25 interaction regulates insulin secretion by controlling secretory granule docking sites in response to glucose levels.
bioRxiv · Jan 13, 2026 · PreprintCell Biology