Cancer BiologyBiomedicine & PharmacotherapyPeer-reviewed
Zebrafish Drug Screening Identifies Erlotinib as an Inhibitor of Wnt/β-Catenin Signaling and Self-Renewal in T-cell Acute Lymphoblastic Leukemia
Majd A. Al‐Hamaly, Anna H. Cox, Meghan G. Haney…·Jessica S. Blackburn
This study identifies Erlotinib as a Wnt/β-catenin inhibitor effective in zebrafish and human cells, reducing leukemia-initiating cell self-renewal and disease progression.