Developmental BiologybioRxivPreprint
Loss of the mitochondrial carrier, SLC25A1, during embryogenesis induces a unique senescence program controlled by p53
Anna Kasprzyk-Pawelec, Mingjun Tan, Raneen Rahhal…·Maria Laura Avantaggiati
This study shows that SLC25A1 deficiency in mice causes senescence via p53-dependent pathways, leading to developmental disorders similar to human D/L-2HGA.
5 citations