Cell BiologybioRxiv
Liver-specification of human iPSC-derived endothelial cells transplanted into mouse liver
Kiryu K. Yap, Jan Schröder, Yi-Wen Gerrand…·Geraldine M. Mitchell
This study transplants human iPSC-derived endothelial cells into mice to generate LSEC-like cells, identifies key transcription factors and markers for LSEC specification, and provides a model for studying liver endothelial development.