Pharmacology & ToxicologyFrontiers in PharmacologyPeer-reviewed
Mechanistic insights into Rho/MRTF inhibition-induced apoptotic events and prevention of drug resistance in melanoma: Implications for the involvement of pirin
Bardees M. Foda, Annika E. Baker, Łukasz Joachimiak…·Richard R. Neubig
This study shows that CCG-257081 overcomes melanoma resistance by inducing apoptosis and inhibiting the Rho/MRTF pathway, with pirin playing a role in this process.
4 citations