ImmunologybioRxivPreprint
The fungal ligand chitin directly binds and signals inflammation dependent on oligomer size and TLR2
Katharina Fuchs, Yamel Cardona Gloria, Olaf-Oliver Wolz…·Alexander N.R. Weber
This study identifies chitin oligomers as the smallest immunologically active motif and TLR2 as the primary receptor for chitin, showing size-dependent signaling and therapeutic potential.