Cancer BiologybioRxivPreprint
Mining the Proteome of Human Ovarian Cancer Extracellular Vesicles Using Thermolysin Proteolysis
Tyler T. Cooper, Jaihui Lui, Olena Bilyk…·Gilles A. Lajoie
This study compares Thermolysin and Trypsin/LysC proteolysis for enhancing proteomic analysis of ovarian cancer extracellular vesicles, finding Thermolysin improves peptide complexity and identifies unique proteins like Ly6E and NODAL.
DOI 10.1101/2024.10.10.617562