Pharmacology & ToxicologybioRxivPreprint
Brg1 regulates fibroblast-myofibroblast transition to promote renal fibrosis
Xiaoyan Wu, Yajun Luo, Aoqi Kang…·Tao Zhang
This study shows Brg1 promotes fibroblast-myofibroblast transition in renal fibrosis and identifies Prune2 and PU.1 as downstream targets, with PFI-3 as a potential antifibrotic drug.
DOI 10.1101/2023.12.22.572996