Cinnamaldehyde interacts with the local anesthetic pocket of the NaV 1.5 channel
Julio Alvarez‐Collazo, Alejandro López‐Requena, Ariel Talavera…·Karel Talavera
This study shows that cinnamaldehyde blocks NaV1.5 channels in a voltage-dependent manner, similar to local anesthetics, and identifies key residues involved in this interaction.