Pharmacology & ToxicologybioRxivPreprint
Mx1-Cre-mediated Rac1 knockout confers multiple protective effects against anthracycline-induced acute normal tissue injury
Pelin Kücük, Sophie Gatzmanga, Jana Aengenvoort…·Gerhard Fritz
This study shows that Rac1 deletion reduces anthracycline-induced organ damage in mice, with effects varying by organ and drug type.
DOI 10.1101/2025.07.03.662930