GeneticsbioRxivPreprint
OPA1 controls mitochondrial dysfunction-driven liver fibrosis in MASLD
Xinting Yu, Pinzhu Huang, Arvo Justice…·Yury V. Popov
The paper identifies OPA1 as a key regulator of liver fibrosis in MASLD by linking mitochondrial dysfunction to fibrotic responses through mito-DAMP release and hepatic stellate cell activation.
DOI 10.64898/2026.09.24.753666