BiochemistrybioRxivPreprint
TDP-43 oligomers detected as initial intermediate species during aggregate formation
Rachel L. French, Ashley N. Reeb, Himani Aligireddy…·Yuna M. Ayala
This study identifies TDP-43 oligomers as early intermediates in aggregation, showing ALS-linked mutations accelerate this process and enhance aggregate propagation.
DOI 10.1101/499343