Targeted delivery of mRNA to the heart via extracellular vesicles or lipid nanoparticles
Muhammad Nawaz, Benyapa Tangruksa, Sepideh Heydarkhan‐Hagvall…·Hadi Valadi
This study compares the efficiency of cardiac-specific extracellular vesicles and lipid nanoparticles in delivering mRNA to the heart, finding that cardiac-specific vesicles are more effective with less liver accumulation.