ImmunologybioRxiv
Longitudinally persistent cerebrospinal fluid B-cells resist treatment in multiple sclerosis
A. L. Greenfield, R. Dandekar, A. Ramesh…·H.- C. von Büdingen
This study identifies persistent B-cell clones in the cerebrospinal fluid of MS patients despite treatment, suggesting therapy-resistant immune mechanisms in the central nervous system.
DOI 10.1172/jci.insight.126599