Cell BiologybioRxiv
Histone deacetylase 6 inhibition promotes microtubule acetylation and facilitates autophagosome-lysosome fusion in dystrophin-deficient mdx mice
A. Agrawal, E. L. Clayton, C. L. Cavazos…·G. G. Rodney
This study shows that inhibiting HDAC6 increases tubulin acetylation and autophagosome-lysosome fusion in dystrophin-deficient mdx mice, improving muscle function and reducing damage.
DOI 10.1111/apha.14243