Author

B. Adane

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Approach:genetic perturbation / CRISPR· 1 Approach:statistical model· 1

Frequent Co-Authors

K. Stegmaier· 2 shared A. Conway· 1 shared A. Letai· 1 shared A. Raimondi· 1 shared A. Robichaud· 1 shared B. A. Leeper· 1 shared B. K. A. Seong· 1 shared C. A. French· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

K. Stegmaier

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2 papers

Recent·Most cited

EZH2 synergizes with BRD4-NUT to drive NUT carcinoma growth through silencing of key tumor suppressor genes

Y. Huang, R. T. Durall, N. M. Luong, H. J. Hertzler, J. Huang, P. C. Gokhale, B. A. Leeper, N. S. Persky, D. E. Root, P. V. Anekal, P. D. Montero Llopis, C. N. David, J. L. Kutok, A. Raimondi, K. Saluja, , C. A. French

This study identifies EZH2 as a dependency in NUT carcinoma, showing that combining EZH2 and BET inhibitors synergistically blocks tumor growth and prolongs survival.

bioRxiv · Aug 15, 2023Cancer Biology

An in vivo CRISPR screening platform for prioritizing therapeutic targets in AML

S. Lin, C. Larrue, B. K. A. Seong, N. V. Dharia, M. Kuljanin, C. Wechsler, G. Kugener, A. Robichaud, A. Conway, T. N. Mashaka, S. Mouche, B. Adane, J. Ryan, J. D. Mancias, S. T. Younger, , K. Stegmaier

This study identifies novel therapeutic targets for AML using an in vivo CRISPR screening platform, revealing SLC5A3 as a metabolic vulnerability and MARCH5 as an apoptosis regulator.

bioRxiv · Dec 28, 2020Cancer Biology