MicrobiologybioRxivPreprint
Identification of a critical horseshoe-shaped region in the nsp5 (Mpro, 3CLpro) protease interdomain loop (IDL) of coronavirus mouse hepatitis virus (MHV)
B. C. Nick, M. C. Pandya, X. Lu…·C. C. Stobart
This study identifies a conserved horseshoe-shaped region in the nsp5 protease interdomain loop of MHV that is essential for viral replication and may serve as a new drug target.
DOI 10.1101/2020.06.18.160671