NeurosciencebioRxivPreprint
Neurovascular mitochondrial susceptibility impacts blood-brain barrier function and behavior
Alexis Mary Crockett, Hania Kébir, M. C. Vélez Colόn…·Jorge Ivan Alvarez
This study shows mitochondrial dysfunction in the blood-brain barrier of 22qDS patients and mice, leading to impaired barrier function and social memory, which is corrected by mitochondrial treatment.