Author

B. Cocom-Chan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Approach:biophysical modeling· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

G. Tran Van Nhieu· 3 shared A. Asnacios· 2 shared A. MAUVIEL· 2 shared B. Mazhar· 2 shared C. BELLO· 2 shared C. Bou-Nader· 2 shared C. Malosse· 2 shared C. Valencia-Gallardo· 2 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCell Biology

G. Tran Van Nhieu

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

IpaA reveals distinct modes of vinculin activation during Shigella invasion and cell-matrix adhesion

B. Cocom-Chan, H. Khakzad, M. KONATE, D. I. AGUILAR, C. BELLO, C. Valencia-Gallardo, Y. Zarrouk, J. FATTACCIOLI, A. MAUVIEL, D. JAVELAUD, G. Tran Van Nhieu

This study shows IpaA activates vinculin in distinct ways during Shigella invasion and cell-matrix adhesion, with different effects on invasion and adhesion.

bioRxiv · Mar 23, 2023 · PreprintCell Biology

Shigella ipaA mediates actin bundling through diffusible vinculin oligomers with activation imprint

C. M. Valencia-Gallardo, D. I. Aguilar, H. Khakzad, B. Cocom-Chan, C. Bou-Nader, C. Velours, Y. Zarrouk, C. Le Clainche, C. Malosse, D. Borges-Lima, N. Quenech'Du, B. Mazhar, S. Essid, M. Fontecave, A. Asnacios, , G. Tran Van Nhieu

This study shows that Shigella IpaA induces vinculin homo-oligomerization, leading to actin bundling and stable cell adhesion independent of force transduction.

bioRxiv · Nov 7, 2022 · PreprintMicrobiology

ipaA triggers vinculin oligomerization to strengthen cell adhesion during Shigella invasion

C. Valencia-Gallardo, D. I. Aguilar Salvador, H. Khazad, C. Bou-Nader, C. Malosse, D. Borges-Lima, C. Bello, B. Cocom-Chan, N. Quenech'Du, B. Mazhar, D. Javelaud, J. Fattaccioli, A. Mauviel, M. Fontecave, A. Asnacios, , G. Tran Van Nhieu

This paper shows that Shigella's IpaA protein causes vinculin to oligomerize, strengthening cell adhesion during bacterial invasion.

bioRxiv · Aug 14, 2020 · PreprintCell Biology