Author

C. Malosse

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:bacteria (other)· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

J. Chamot-Rooke· 4 shared A. Asnacios· 2 shared B. Cocom-Chan· 2 shared B. Mazhar· 2 shared C. Bou-Nader· 2 shared D. Borges-Lima· 2 shared G. Tran Van Nhieu· 2 shared L. Malmstrom· 2 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersMicrobiology

J. Chamot-Rooke

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Shigella ipaA mediates actin bundling through diffusible vinculin oligomers with activation imprint

C. M. Valencia-Gallardo, D. I. Aguilar, H. Khakzad, B. Cocom-Chan, C. Bou-Nader, C. Velours, Y. Zarrouk, C. Le Clainche, C. Malosse, D. Borges-Lima, N. Quenech'Du, B. Mazhar, S. Essid, M. Fontecave, A. Asnacios, , G. Tran Van Nhieu

This study shows that Shigella IpaA induces vinculin homo-oligomerization, leading to actin bundling and stable cell adhesion independent of force transduction.

bioRxiv · Nov 7, 2022 · PreprintMicrobiology

Structural and molecular determinants for the interaction of ExbB from Serratia marcescens and HasB, a TonB paralog

V. Biou, R. J. D. Adaixo, M. Chami, P.-D. Coureux, B. Laurent, V. Y. Ntsogo Enguene, G. Cardoso de Amorim, N. Izadi-Pruneyre, C. Malosse, J. Chamot-Rooke, H. Stahlberg, P. Delepelaire

The paper determines the cryo-EM structures of ExbBSm and ExbB-ExbDSm complex, identifies key residues for function and interaction with TonB/HasB, and reveals the role of ExbBSm extension in heme acquisition.

bioRxiv · Apr 21, 2021Microbiology

ipaA triggers vinculin oligomerization to strengthen cell adhesion during Shigella invasion

C. Valencia-Gallardo, D. I. Aguilar Salvador, H. Khazad, C. Bou-Nader, C. Malosse, D. Borges-Lima, C. Bello, B. Cocom-Chan, N. Quenech'Du, B. Mazhar, D. Javelaud, J. Fattaccioli, A. Mauviel, M. Fontecave, A. Asnacios, , G. Tran Van Nhieu

This paper shows that Shigella's IpaA protein causes vinculin to oligomerize, strengthening cell adhesion during bacterial invasion.

bioRxiv · Aug 14, 2020 · PreprintCell Biology

Crippling the bacterial cell wall molecular machinery

A. H. Williams, I. Boneca, R. Wheeler, A.-E. Deghmane, I. Santecchia, F. Impens, P. A. D. Bastos, S. Hicham, M. Moya Nilges, C. Malosse, J. Chamot-Rooke, A. Haouz, W. P. Robins, M.-K. Taha

This study identifies the role of lytic transglycosylase LtgA in bacterial cell wall integrity and shows that targeting it can impair Neisseria meningitidis fitness during infection.

bioRxiv · Apr 12, 2019 · PreprintBiochemistry