In vivo optical metabolic imaging of long-chain fatty acid uptake in orthotopic models of triple negative breast cancer
M. C. Madonna, J. E. Duer, J. V. Lee, J. Williams, B. Avsaroglu, C. Zhu, R. Deutsch, R. Wang, B. Crouch, M. Hirschey, A. Goga, N. Ramanujam
This study develops an in vivo optical imaging method to quantify long-chain fatty acid uptake in breast cancer models, showing reduced uptake with MYC downregulation and increased uptake with tumor aggressiveness.
bioRxiv · Nov 2, 2020Bioengineering