B. Gautier

Targeting PD-L1 in solid cancer with myeloid cells expressing a CAR-like immune receptor

This study demonstrates that engineered myeloid cells expressing a PD-1-based CAR-like receptor can recognize and attack PD-L1+ solid tumors, enhancing phagocytosis and slowing tumor growth in vivo.

AAV2/9-mediated gene transfer into murine lacrimal gland leads to a long-term targeted tear film modification

This study uses AAV2/9 gene transfer to modify tear film composition in mice, showing long-term secretion of nerve growth factor to support corneal health.