Author

B. Guan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1 Approach:machine learning (classical)· 1 Organism:plant (other)· 1 Research Focus:protein design· 1 Assay:protein structure· 1

Frequent Co-Authors

R. L. Evans· 2 shared A. Y. L. LEUNG· 1 shared B. Jones· 1 shared C. Luo· 1 shared C. Pierce· 1 shared C. T. Pierce· 1 shared C. Wilmot· 1 shared D. Chaudhury· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersBioengineering

R. L. Evans

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Author profile →

3 papers

Recent·Most cited

Designing Efficient Enzymes: Eight Predicted Mutations Convert a Hydroxynitrile Lyase into an Efficient Esterase

G. Casadevall, C. T. Pierce, B. Guan, J. Iglesias-Fernandez, H.-Y. Lim, L. R. Greenberg, M. E. Walsh, K. Shi, W. R. Gordon, H. Aihara, R. L. Evans, R. J. Kazlauskas, S. Osuna

The paper identifies eight mutations that convert a hydroxynitrile lyase into an efficient esterase by correcting structural differences using shortest path maps.

bioRxiv · Aug 23, 2023 · PreprintBioengineering

Deciphering 3D Human Sphygmopalpation Pulse Patterns using "X-ray" Images Acquired from Tactile Robotic Fingers

K. W. KONG, H.-y. CHAN, J. XIE, F. C. S. LEE, A. Y. L. LEUNG, B. GUAN, J. SHEN, V. C.-W. TAAM WONG, W. J. LI

This paper develops a robotic platform with tactile sensing and machine learning to digitize and classify 3D human pulse patterns, achieving 98.7% and 84.2% classification rates for three TCM pulse types.

bioRxiv · Jan 10, 2021 · PreprintBioengineering

Larger active site in an ancestral hydroxynitrile lyase increases catalytically promiscuous esterase activity

B. Jones, R. L. Evans, N. Mylrea, D. Chaudhury, C. Luo, C. Pierce, B. Guan, W. Gordon, C. Wilmot, R. Kazlauskas

This paper reconstructs an ancestral hydroxynitrile lyase, HNL1, which has a larger active site and increased catalytic promiscuity compared to modern HbHNL.

bioRxiv · Apr 6, 2020Biochemistry