YB-1 IS REQUIRED FOR THE GENESIS AND METASTATIC CAPACITY OF HUMAN BREAST CANCER
S. Lefort, A. El-Naggar, S. Tan, S. Colborne, G. L. Negri, D. Pellacani, M. Hirst, B. Gusterson, G. B. Morin, P. H. Sorensen, C. J. Eaves
This study shows YB-1 is essential for human breast cancer growth and metastasis, as its knockdown inhibits tumor formation and lung colonization in mice.
bioRxiv · Nov 20, 2020 · PreprintCancer Biology