Productive and latent HIV infections originate in resting CD4+ T cells
S. Wietgrefe, J. Anderson, L. Duan, P. J. Southern, P. Zuck, G. Wu, B. Howell, C. Reilly, E. Kroon, S. Chottanapund, S. Buranapraditkun, C. Sacdalan, N. Tulmethakaan, D. J. Colby, N. Chomchey, , A. T. Haase
This study shows that resting CD4+ T cells are the initial source of both productive and latent HIV infections in the earliest stages of detectable infection.
bioRxiv · Aug 26, 2022 · PreprintImmunology