Author

M. Dube

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 6 Research Focus:cell type annotation· 5 Approach:experimental assay· 5 Assay:bulk RNA-seq· 3 Assay:flow cytometry· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:clustering· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

D. E. Kaufmann· 6 shared G. Sannier· 5 shared A. Finzi· 4 shared C. Tremblay· 4 shared J. Niessl· 4 shared N. Brassard· 4 shared A. Nicolas· 3 shared C. Bourassa· 3 shared

Activity by Year

2021-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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6 shared papersImmunology

D. E. Kaufmann

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6 papers

Recent·Most cited

CD4 downregulation precedes Env expression and protects HIV-1-infected cells from ADCC mediated by non-neutralizing antibodies

J. Richard, G. Sannier, L. Zhu, J. Prevost, L. Marchitto, M. Benlarbi, G. Beaudoin-Bussieres, K. Hongil, Y. Sun, D. A. Chatterjee, H. Medjahed, C. Bourassa, G.-G. Delgado, M. Dube, F. Kirchhoff, , A. Finzi

The paper shows CD4 downregulation precedes Env expression in HIV-1-infected cells, making them resistant to non-neutralizing antibody-mediated ADCC.

bioRxiv · May 1, 2024Microbiology

A third SARS-CoV-2 mRNA vaccine dose in people receiving hemodialysis overcomes B cell defects but elicits a skewed CD4+ T cell profile

G. Sannier, A. Nicolas, M. Dube, L. Marchitto, M. Nayrac, O. Tastet, A. Tauzin, R. Lima-Barbosa, M. Laporte, R. Cloutier, A. S. Flores, M. Boutin, S. Y. Gong, M. Benlarbi, S. Ding, , D. E. Kaufmann

bioRxiv · Sep 5, 2022Immunology

A long interval between priming and boosting SARS-CoV-2 mRNA vaccine doses enhances B cell responses with limited impact on T cell immunity

A. Nicolas, G. Sannier, M. Dube, M. Nayrac, M. M. Painter, R. R. Goel, M. Laporte, H. R. Medjahed, J. Williams, N. Brassard, J. Niessl, L. Gokool, C. Morrisseau, P. Arlotto, C. Tremblay, , D. E. Kaufmann

This study shows that a longer interval between SARS-CoV-2 mRNA vaccine doses enhances B cell responses but has minimal impact on T cell immunity.

bioRxiv · Aug 3, 2022 · PreprintImmunology

Detecting sources of immune activation and viral rebound in HIV infection

S. Wietgrefe, L. Duan, J. Anderson, G. Marques, M. Sanders, N. W. Cummins, A. D. Badley, C. Dobrowolski, J. Karn, A. Pagliuzza, N. Chomont, G. Sannier, M. Dube, D. E. Kaufmann, P. Zuck, , A. T. Haase

The paper compares assays for detecting HIV-producing cells and p24 during ART to identify sources of immune activation and viral rebound.

bioRxiv · Jun 8, 2022Immunology

Temporal associations of B and T cell immunity with robust vaccine responsiveness in a 16-week interval BNT162b2 regimen

M. Nayrac, M. Dube, G. Sannier, A. Nicolas, L. Marchitto, O. Tastet, A. Tauzin, N. Brassard, G. Beaudoin-Bussieres, D. Vezina, S. Y. Gong, M. Benlarbi, R. Gasser, A. Laumaea, C. Bourassa, , D. E. Kaufmann

The paper examines B and T cell immunity responses to a 16-week interval BNT162b2 vaccine regimen, finding robust immune memory and functional associations between immune components.

bioRxiv · Dec 18, 2021Immunology

Immune checkpoint expression on HIV-specific CD4+ T cells and response to their blockade are dependent on lineage and function

E. Brunet-Ratnasingham, A. Morou, M. Dube, J. Niessl, A. E. Baxter, O. Tastet, N. Brassard, G. Ortega-Delgado, R. Charlebois, G. J. Freeman, C. Tremblay, J.-P. Routy, D. E. Kaufmann

bioRxiv · Sep 23, 2021Immunology