The highly and perpetually upregulated thyroglobulin gene is a hallmark of functional thyrocytes
S. Ullrich, S. Leidescher, Y. Feodorova, K. Thanisch, J.-B. Fini, B. Kaspers, F. Weber, B. Markova, D. Fuehrer, M. Romitti, S. Krebs, H. Blum, H. Leonhardt, S. Costagliola, H. Heuer, I. Solovei
The paper identifies thyroglobulin gene (Tg) as a permanently upregulated gene in thyrocytes across vertebrates, providing insights into mechanisms of sustained transcriptional activation.
bioRxiv · Jun 23, 2023Cell Biology