Author

B. Lenhard

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

N. Cvetesic· 3 shared A. Martinez-Sanchez· 2 shared G. A. Rutter· 2 shared G. Pizza· 2 shared N. Haberman· 2 shared A. G. Fisher· 1 shared A. M. J. Shapiro· 1 shared B. HASTOY· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersCell Biology

N. Cvetesic

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3 papers

Recent·Most cited

Liver kinase B1 (LKB1) regulates the epigenetic landscape of mouse pancreatic beta cells

N. Haberman, R. Cheung, G. Pizza, N. Cvetesic, D. Nagy, H. Maude, L. Blazquez, B. Lenhard, I. Cebola, G. A. Rutter, A. Martinez-Sanchez

This study shows that LKB1 deletion in mouse pancreatic beta cells causes widespread chromatin accessibility changes and affects gene expression, including neuronal genes.

bioRxiv · May 13, 2024Cell Biology

Roles for the long non-coding RNA Pax6os1/PAX6-AS1 in pancreatic beta cell identity and function.

L. Lopez-Noriega, R. M. Callingham, A. Martinez-sanchez, S. Nawaz, G. Pizza, N. Haberman, N. Cvetesic, M.-S. Nguyen-Tu, B. Lenhard, P. Marchetti, L. Piemonti, E. J. P. de Koning, A. M. J. Shapiro, P. R. Johnson, I. Leclerc, , G. A. Rutter

This study investigates the role of Pax6os1/PAX6-AS1 in beta cell identity and function, finding that its upregulation in diabetes contributes to impaired functionality and that targeting it may improve glucose homeostasis.

bioRxiv · Jul 17, 2020 · PreprintCell Biology

Partial rescue of neuronal genes deregulated in Cornelia de Lange Syndrome by cohesin

F. D. Weiss, L. Calderon, Y.-F. Wang, R. Georgieva, Y. Guo, N. Cvetesic, M. Kaur, G. Dharmalingam, I. D. Krantz, B. Lenhard, A. G. Fisher, M. Merkenschlager

The paper investigates cohesin's role in neuronal gene expression in CdLS by analyzing transcriptomes and showing partial rescue of gene deregulation through cohesin reconstitution.

bioRxiv · Jun 6, 2020Cell Biology