Author

G. Dharmalingam

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. G. Fisher· 1 shared A. I. Choudhury· 1 shared A. Paccanaro· 1 shared A. Uren· 1 shared B. Iadarola· 1 shared B. J. Bolt· 1 shared B. Lenhard· 1 shared D. Heide· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperCell Biology

A. G. Fisher

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Author profile →

3 papers

Recent·Most cited

Ribosomal S6 kinase 1 regulates inflammaging via the senescence secretome

S. Gallage, E. E. Irvine, S. Pedroni, J. E. Barragan Avila, S. Khadayate, J. Pombo, S. Brookes, D. Heide, G. Dharmalingam, A. I. Choudhury, N. Herranz, S. Vernia, M. Heikenwalder, J. Gil, D. J. Withers

This study shows that S6K1 deletion reduces inflammation and immune infiltration in aged livers, suggesting it suppresses the inflammatory SASP, contributing to healthspan benefits.

bioRxiv · Oct 17, 2023Physiology

Partial rescue of neuronal genes deregulated in Cornelia de Lange Syndrome by cohesin

F. D. Weiss, L. Calderon, Y.-F. Wang, R. Georgieva, Y. Guo, N. Cvetesic, M. Kaur, G. Dharmalingam, I. D. Krantz, B. Lenhard, A. G. Fisher, M. Merkenschlager

The paper investigates cohesin's role in neuronal gene expression in CdLS by analyzing transcriptomes and showing partial rescue of gene deregulation through cohesin reconstitution.

bioRxiv · Jun 6, 2020Cell Biology

Tracking Subclonal Mutation Frequencies Throughout Lymphomagenesis Identifies Cancer Drivers in Mouse Models of Lymphoma.

P. Webster, J. C. Dawes, H. Dewchand, K. Takacs, B. Iadarola, B. J. Bolt, J. J. Caceres, J. Kaczor, L. Game, T. Adejumo, J. Elliott, K. Naresh, G. Tan, G. Dharmalingam, A. Paccanaro, A. Uren

The paper tracks subclonal mutation frequencies in mouse lymphoma models to identify cancer drivers and demonstrates negative selection of potentially deleterious mutations.

bioRxiv · Jun 29, 2017Cancer Biology