Nitric oxide prevents aortic valve calcification by S-nitrosylation of USP9X to activate NOTCH signaling
U. Majumdar, S. Manivannan, M. Basu, Y. Ueyama, M. C. Blaser, E. Cameron, M. R. McDermott, J. Lincoln, S. E. Cole, S. Wood, E. Aikawa, B. Lilly, V. Garg
The paper shows nitric oxide prevents aortic valve calcification by S-nitrosylating USP9X to activate NOTCH signaling in porcine valve cells and mice.
bioRxiv · Aug 15, 2020Cell Biology