Cell BiologybioRxiv
Nitric oxide prevents aortic valve calcification by S-nitrosylation of USP9X to activate NOTCH signaling
U. Majumdar, S. Manivannan, M. Basu…·V. Garg
The paper shows nitric oxide prevents aortic valve calcification by S-nitrosylating USP9X to activate NOTCH signaling in porcine valve cells and mice.
DOI 10.1126/sciadv.abe3706