Identification of Drugs Blocking SARS-CoV-2 Infection using Human Pluripotent Stem Cell-derived Colonic Organoids
X. Duan, Y. Han, L. Yang, B. Nilsson, P. Wang, T. Zhang, X. Wang, D. Xu, J. Z. Xiang, s. uhl, Y. Huang, H. Chen, H. Wang, B. R. tenOever, R. E. Schwartz, , T. R. Evans
This study uses human pluripotent stem cell-derived colonic organoids to identify drugs that block SARS-CoV-2 infection, finding mycophenolic acid and quinacrine dihydrochloride effective in vitro and in vivo.
bioRxiv · May 2, 2020 · PreprintMicrobiology