MicrobiologybioRxiv
RstA is a Major Regulator of Clostridioides difficile Toxin Production and Motility
A. N. Edwards, B. R. Anjuwon-Foster, S. M. McBride
This paper identifies RstA as a transcriptional repressor that inhibits toxin gene expression and positive regulators in C. difficile, revealing its role in controlling toxin production through direct DNA binding and autoregulation.
DOI 10.1128/mbio.01991-18