ImmunologybioRxiv
Interleukin-10 and Small Molecule SHIP1 Allosteric Regulators Trigger Anti-Inflammatory Effects Through SHIP1/STAT3 Complexes
T. C. Chamberlain, S. T. Cheung, J. S. J. Yoon…·A. L.-F. Mui
The paper shows IL10 induces a SHIP1/STAT3 complex in macrophages, and SHIP1 activators mimic IL10's anti-inflammatory effects in colitis.
DOI 10.1016/j.isci.2020.101433