Author

B. Salzer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

O. Dushek· 2 shared A. Plach· 1 shared D. H. Busch· 1 shared H. Stockinger· 1 shared I. Doel-Perez· 1 shared J. A. Siller-Farfan· 1 shared J. B. Huppa· 1 shared J. Burton· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

O. Dushek

Mutual co-authors in cluster

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2 papers

Recent·Most cited

TCR/CD3-based synthetic antigen receptors (TCC) convey superior antigen sensitivity combined with high fidelity of activation

T. Peters, V. Muehlgrabner, R. M. H. Velasco Cardenas, R. Platzer, J. Gohring, B. Salzer, A. Plach, M. Hoehrhan, I. Doel-Perez, V. D. R. Goncalves, J. S. Farfan, M. Lehner, H. Stockinger, W. W. Schamel, K. Schober, , J. B. Huppa

This study shows TCR/CD3-based synthetic antigen receptors (TCC) have superior antigen sensitivity and activation fidelity compared to second-generation CARs.

bioRxiv · Mar 16, 2023 · PreprintImmunology

Inefficient exploitation of accessory receptors reduces the sensitivity of chimeric antigen receptors.

J. Burton, J. A. Siller-Farfan, J. Pettmann, B. Salzer, M. Kutuzov, P. A. van der Merwe, O. Dushek

This study shows that CARs have lower antigen sensitivity than TCRs due to inefficient use of accessory receptors, and demonstrates ways to improve this sensitivity.

bioRxiv · Oct 26, 2021Immunology