Bacteriophage therapy for the treatment of Mycobacterium tuberculosis infections in humanized mice
G. Yi, F. Yang, A. Labani-Motlagh, J. D. Moreira, D. Ansari, J. A. Bohorquez, S. Patel, F. Spagnolo, J. Florence, A. Vankayalapati, R. Vankayalapati, J. J. D. J. Dennehy, B. Samten
This study tests three bacteriophages against Mtb and finds that DS6A effectively kills Mtb in culture and infected macrophages, improving survival and reducing bacterial load in humanized mice.
bioRxiv · Jan 23, 2023Microbiology