Cell BiologybioRxiv
Phospholipase Cβ2 Promotes Vascular Endothelial Growth Factor Induced Vascular Permeability
K. N. Phoenix, Z. Yue, L. Yue…·K. P. Claffey
This study identifies PLCβ2 as a key regulator of VEGF-induced vascular permeability by modulating calcium flux and PIP2 levels, showing therapeutic potential for diseases involving vascular leakage.
DOI 10.1161/atvbaha.122.317645