Pharmacology & ToxicologybioRxiv
Human islet expression levels of Prostaglandin E2 synthetic enzymes, but not prostaglandin EP3 receptor, are positively correlated with markers of β-cell function and mass in non-diabetic obesity
N. A. Truchan, R. J. Fenske, H. K. Sandhu…·M. E. Kimple
The paper examines the relationship between PGE2 production and β-cell function in non-diabetic obesity, finding that PGE2 synthetic enzymes correlate with β-cell mass and function, while EP3 receptor does not.
DOI 10.1021/acsptsci.1c00045