Molecular mechanics underlying flat-to-round membrane budding in live secretory cells
W. Shin, B. Zucker, N. Kundu, S. H. Lee, B. Shi, X. Guo, C. Y. Chan, J. T. Harrison, J. M. Turechek, J. E. Hinshaw, M. Kozlov, L.-G. Wu
The paper identifies actin filaments and dynamin as key forces mediating non-coated membrane budding in live cells, revealing mechanisms that transform flat membranes into vesicles.
bioRxiv · Feb 2, 2022Cell Biology