Author

B. Zuckerbraun

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Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

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D. Nolfi-Donegan· 1 shared G. K. Annarapu· 1 shared L. Kohut· 1 shared M. Reynolds· 1 shared S. Shiva· 1 shared Y. Wang· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperCell Biology

D. Nolfi-Donegan

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1 paper

Recent·Most cited

Cell BiologybioRxivAug 2, 2021

Heme stimulates platelet mitochondrial oxidant production via the activation of toll-like receptor 4 signaling to mediate targeted granule secretion

G. K. Annarapu, D. Nolfi-Donegan, M. Reynolds…·S. Shiva

This study shows that heme activates platelet TLR4 signaling, leading to mitochondrial ROS production and targeted granule secretion, with implications for thrombo-inflammatory responses.

DOI 10.1016/j.redox.2021.102205

humanmouse

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