BiochemistryJournal of Biological ChemistryPeer-reviewed
Thymine DNA Glycosylase Binds to R-Loops and Excises 5-Formyl and 5-Carboxyl Cytosine from DNA/RNA Hybrids
Baiyu Zhu, Lakshmi Swarna Mukhi Pidugu, Mary E. Cook…·Jonathan T. Sczepanski
This study shows that TDG binds R-loops and removes 5-formyl and 5-carboxyl cytosine from DNA/RNA hybrids, supporting a role for R-loops in DNA demethylation.
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